Treated with an organic antimicrobial active ingredient, the Clean’Safe notebook cover stops the spread of bacteria and viruses, eliminating them by more than 99%. It lasts for the lifetime of the product! This additive is not bioaccumulative and is harmless to health. Featuring 100% recyclable materials, Clean’Safe notebooks include our outstanding Clairefontaine® brushed vellum 90gsm paper.The pressboard cover is treated with a quaternary ammonium-based biocide, an organic antimicrobial additive. FDA (Food and Drug Administration) and BFR 36 (Paper & Board for food contact) approved, this additive is not bioaccumulative and safe for health. It is also frequently used in disinfectant gels.